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Physical dependence is a state that develops as a result of physiological adaptation in response to repeated drug use, manifested by withdrawal signs and symptoms after abrupt discontinuation or a significant dose reduction of a drug

1 2 "A synthetic cannabinoid FDU-NNEI, two 2 H -indazole isomers of synthetic cannabinoids AB-CHMINACA and NNEI indazole analog (MN-18), a phenethylamine derivative N -OH-EDMA, and a cathinone derivative dimethoxy--PHP, newly identified in illegal products"

The meningococcal genome has a glutamine synthetase but lacks a functional glutamate synthase and, therefore, a Glutamine Synthetase (GS)/Glutamine Oxoglutarate Aminotransferase (GOGAT) cycle, suggesting a major role for NADP-GDH in ammonia assimilation

10.15932/j.0253-9713.2019.12.009 20 GongX

doi: 10.3390/nu11010169

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