DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE alcohol 662 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC)

662 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

126 Purity (HPLC) >= 95% Solubility DMSO

The primary aliphatic amine of the red-fluorescentSulforhodamine 101 cadaverine (Texas Red C)can be reversibly coupled to aldehydes and ketones to form a Schiff base - which can be reduced to a stable amine derivative by sodium borohydride (NaBH4) or sodium cyanoborohydride (NaCNH3) to form new biotinylated probes

461 Purity (HPLC) >= 95% Solubility DMSO

enabling researchers to use both SNAP-tag and CLIP-tag in the same experiment

DBCO-Propionyl-Val-Cit-PAB(m-PEG8)-MMAE alcohol 662 SMILES OC(=O)CN1CCN(CC(O)=O)CCN(CC(=O)NCCOCCOCCOCCN=[N+]=[N-])CCN(CC(O)=O)CC1 Purity (HPLC)SOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is monomethyl auristatin E (MMAE), a highly potent antimitotic agent that inhibits tubulin polymerization, leading to cell cycle arrest and subsequent apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing