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From the well-characterized monogenic optic neuropathies and Friedreichs ataxia to the complex, multifactorial pathology of Alzheimers and Parkinsons diseases, the shared themes of bioenergetic failure, disrupted dynamics, defective quality control, and neuroinflammatory amplification underscore the central role of mitochondrial health in neuronal survival

J Neurochem 76:627636 Hirrlinger J, Resch A, Gutterer JM, Dringen R (2002a) Oligodendroglial cells in culture effectively dispose of exogenous hydrogen peroxide: comparison with cultured neurones, astroglial and microglial cells