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The metabolism of cystine/cysteine metabolism serves an important role in the onset and progression of TNBC and may be closely associated with patient responses to therapy

In mammalian cells, cystine (the oxidized form of cysteine) is imported into cells by system Xc for subsequent GLC (glutamate-cysteine ligase)-mediated GSH production

This has made it one of the most directly relevant compounds in aging research

As well, GSH detoxifies many agents that can induce the mPT in brain mitochondria including 4-hydroxyhexenal (a lipid peroxide) [39]

The best antioxidant strategy is a team, not a solo player

Conversely, the variation observed across different gene groups indicates that functional differences among the rice HPPD, HPT, VTE1, and VTE4 proteins evolved gradually