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2 Materials and methods 2.1 Materials and reagents We used commercially available reagents and solvents without further purification

Genetic studies have demonstrated that enhanced NRF2 expression significantly attenuates disease progression in EAE models (Kobayashi et al., 2016)

Cells 5 , 17 (2016)

Then 4.4 ml of TEA was added to the solution to adjust the pH

The CNS compartments are tightly sealed from the changeable milieu of blood by the BBB as well as the bloodCSF barrier (BCSFB)

Buckwheat peptides also activate AMPK signaling, which improves fatty acid oxidation, enhances insulin sensitivity, and reduces hepatic lipogenesis, supporting their anti-diabetic potential [37]