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8.1 Antioxidant nanoparticles The OS is characterized by an imbalance between the generation of ROS and the brains antioxidant defenses, which plays a crucial role in the pathogenesis of PD

Immunoprecipitation and Western blot HEK293T cells were collected and lysed in lysis buffer (50 mM Tris, pH 8.0, 150 mM NaCl, 0.5% Triton X-100, 10% glycerol, protease inhibitors and benzonase) and incubated on ice for 30 min

Under MPP+ treatment, HIF-1 expression was elevated, and PGC-1 expression was reduced, consistent with ref

Because HT usually accompanies patients for life and is difficult to recover, which often seriously affects the normal work and quality of life of patients