Fmoc-Val-Cit-PAB(m-PEG8) 4' CC-92480 promotes rapid and extensive

CC-92480 promotes rapid and extensive degradation of Aiolos/Ikaros than s lenalidomide and pomalidomide

866 SMILES CC(C)(C)OC(=O)CN1CCN(CC(=O)NCCOCCO)CCN(CC(=O)OC(C)(C)C)CCN(CC(=O)OC(C)(C)C)CC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Product Name Lenalidomide-C3-OH Synonyms Lenalidomide-4'-C3-OH CAS Number 2301126-97-4 Related CAS Molecular Formula C16H19N3O4 Molecular Weight 317

376 SMILES OC(=O)C1CCN(CC1)C1=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

374 Purity (HPLC) >= 95% Solubility DMSO

Fmoc-Val-Cit-PAB(m-PEG8) 4' CC-92480 promotes rapid and extensiveSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. Derived from established ADC linker architectures, SOLU KNEX ADC linkers integrate solubilizing moietiessuch as PEG, amine containing groups, or polysarcosine (PSAR), to enhance aqueous solubility. Solubility and physicochemical properties can be finely tuned