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Funding This study was supported by grants from the National Natural Science Foundation of China (82570731, 82170627), Basic-clinical integration innovation project of the Xian Jiaotong University (YXJLRH2022042, YXJLRH2022048), Key Research and Development Program of Shaanxi (2023-YBSF-350, 2024SF-YBXM-117) and Outstanding Youth Fund of Xian Jiaotong University (2022YQPY04), Institutional Foundation of The First Affiliated Hospital of Xian Jiaotong University (2021ZYTS-36, 2022MS-27)

In this study, RVX reduced testicular MDA and elevated GPx content, revealing that its anti-oxidant effect mediated its protection against testicular IR

Notably, in most countries PAC is freely sold as an OTC drug, raising the risk of unintentional abuse and increased adverse effects ( No answer can be given to the above open questions because PAC efficacy/adverse effects, unlike most of the drugs repositioned for COVID-19 therapy, have not yet been evaluated in controlled clinical trials or analyzed through retrospective analyses

CPPs have been used in animal cells to deliver genome-editing elements as RNPs non-biolistically, and these short, positively charged peptides were shown to translocate across cell membranes with high delivery efficiencies (Liu et al., 2014

n-Myc is expressed in neural tissues and during the early phases of hematopoietic development, with important value in early tumor therapy (107)

PMID: 115 SannaSVan ZuydamNRMahajanAKurilshikovAVich VilaAVsaUet al