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Notably, tobacco carcinogen exposure led to significant changes in the gut and lung microbiomes, particularly in species like Odoribacter , Alistipes , Akkermansia , and Ruminococcus , which correlated with LUAD development and immunotherapeutic response

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DeCicca said that if Indianans start to purchase their cigarettes across the border, in Kentucky, for example, "such behavior would mitigate any potential health benefits." "It seems likely that substituting to vaping, and other forms of nicotine delivery, will be more prevalent, especially among younger smokers," he added

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