PC-6 dbco-propionyl BG-N3 is a SNAP-tag substrate

BG-N3 is a SNAP-tag substrate containg an azide group for click chemistry applications

461 Purity (HPLC) >= 95% Solubility DMSO

CP-DOTA-tris(t-Bu) is a SNAP-tag substrate containg a precursor of the macrocyclic chelator DOTA

118 Purity (HPLC) >= 95% Solubility DMSO

314 SMILES C(CN1CCNCC1)N1CCNCC1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

PC-6 dbco-propionyl BG-N3 is a SNAP-tag substratePC 6 is a specially designed fluorescent probe for detecting SARM1 activity, built by conjugating a styryl donor group to a pyridine acceptor to form a donoracceptor system. It functions through SARM1s base exchange reaction, where PC 6 is converted into a positively charged product (PAD6) upon incorporation into NAD, leading to strong intramolecular charge transfer and a large fluorescence shift (from ~430 nm to ~520 nm). Among a series of related