Sulfo-CA-SiR Size:10nmol preventing it from forming a

preventing it from forming a covalent bond with the Halo-tag protein

where the Val-Cit-PAB motif enables enzyme-cleavable release of MMAE inside target cells

Product Name: 5-FAM Synonyms: 5-Carboxyfluorescein CAS Number: 76823-03-5 Molecular Formula: C21H12O7 Molecular Weight: 376

523 SMILES OC(=O)CCOCCOCCOCCOCCNC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

71 SMILES CC1=C(SC=N1)C1=CC=C(CNC(=O)[C@@H]2C[C@@H](O)CN2C(=O)[C@@H](NC(=O)COCCOCCOCCOCCBr)C(C)(C)C)C=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Sulfo-CA-SiR Size:10nmol preventing it from forming aHaloTag is a self labeling protein tag engineered from the haloalkane dehalogenase DhaA, originally isolated from Rhodococcus rhodochrous. Its active site binds chloroalkane (CA)substrates, forming an irreversible covalent bond. This stable linkage between the HaloTag protein and its ligand enables rapid and efficient isolation and purification of tagged proteins. Sulfo CA SiR is a sulfonated HaloTag substrate featuring a sulfonate group on the amide