DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan dbco-lys-m-PEG4 The water soluble 5-FAM PEG3

The water soluble 5-FAM PEG3 alkyne has a long PEG3 spacer that separates the dye carboxyfluorescein (commonly known as FAM) from the terminal acetylene group

12 SMILES: [2H]C([2H])([2H])OC1=CC=C(C=C1)B1OC(C)(C)C(C)(C)O1 Isotopic Enrichment: 98 atom % D Purity (HPLC): ≥ 95% Shipping Conditions: room temperature Storage Conditions: Refrigerated Regulatory Statement: For Research Use Only

Product Name MC-Val-Cit-PAB-PNP Synonyms MC-VC-PAB-PNP

5(6)-TAMRA cadaverine is a useful reagent for modifying carboxy groups via EDC-mediated reactions

354 SMILES OCCOCC(=O)NC1=C2CN(C3CCC(=O)NC3=O)C(=O)C2=CC=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

DBCO-Lys(m-PEG4)-Val-Cit-PAB(m-PEG8)-Exatecan dbco-lys-m-PEG4 The water soluble 5-FAM PEG3SOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a DBCO Lys(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. DBCO is a strained alkyne commonly used in copper free click chemistry, specifically in the strain promoted azide alkyne cycloaddition (SPAAC) reaction. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further