Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) peg6 Product Name DOTA-tris(t-Bu)ester-C1-acid Synonyms CAS

Product Name DOTA-tris(t-Bu)ester-C1-acid Synonyms CAS Number 192635-92-0 Related CAS Molecular Formula C30H55N5O9 Molecular Weight 629

Product Name Lenalidomide-PEG3-C2-acid Synonyms Lenalidomide-4'-PEG3-C2-acid CAS Number 2399454-54-5 Related CAS Molecular Formula C22H29N3O8 Molecular Weight 463

Contains an E3 ligase ligand with PEG linker and terminal amine

Abdul-Hadi

Product Name Mal-Lys(m-PEG4)-Val-Cit-PAB(m-PEG4)-Exatecan Synonyms CAS Number Related CAS Molecular Formula C73H100FN11O21 Molecular Weight 1486

Mal-Acetyl-Dap(m-PEG4)-Val-Cit-PAB(m-PEG8) peg6 Product Name DOTA-tris(t-Bu)ester-C1-acid Synonyms CASSOLU KNEX cleavable linker features a Val Cit dipeptide. In this product, a Mal Acetyl Dap(m PEG4) moiety replaces the conventional maleimidocaproyl (MC) unit to enhance aqueous solubility. The Mal Acetyl group may also improve retro Michael addition stability during antibody conjugation. Additionally, m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to further increase aqueous solubility. Derived from established