Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Pomalidomide-CO-C2-alkyne Synonyms Pomalidomide-4'-CO-C2-alkyne

Product Name Pomalidomide-CO-C2-alkyne Synonyms Pomalidomide-4'-CO-C2-alkyne CAS Number 2408797-68-0 Related CAS Molecular Formula C18H15N3O5 Molecular Weight 353

415 Purity (HPLC) >= 95% Solubility DMSO

E7820 induce targeted degradation of the splicing factor RBM39 through recruitment of the E3 ubiquitin ligase CRL4DCAF15

Product Name HQ461 Synonyms CAS Number 1226443-41-9 Related CAS Molecular Formula C15H15N5OS2 Molecular Weight 345

5(6)-FAM PEG3 azide is an excellent alkyne-reactive fluorescent reagent for labeling alkyne-containing biological molecules through click chemistry

Azide-Propionyl-Val-Cit-PAB(m-PEG8)-Exatecan Size:5mg Product Name Pomalidomide-CO-C2-alkyne Synonyms Pomalidomide-4'-CO-C2-alkyneSOLU KNEX cleavable linker features a Val Cit dipeptide. m PEG8 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I inhibitor derived from camptothecin, which induces DNA damage by stabilizing the topoisomerase IDNA complex, resulting in cell cycle arrest and apoptosis. Derived from established ADC linker architectures, SOLU KNEX ADC