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Class I FINs activate ferroptosis by depleting intracellular GSH by inhibiting system X c - [17, 95, 103, 104]

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They are a dynamic equilibrium process catalyzed by an enzyme called glutathione reductase (GR)

Carey et al

J Cell Mol Med

The WHO recommends salt iodization as the preferred strategy to eradicate IDD [19], and several countries have adopted salt-iodization programs, successfully preventing IDDs and improving nutritional iodine status at a population level [38, 39]