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536 When monocytes are stimulated with Mycobacterium bovis BCG cell wall, they induce ZIP8 expression, suggesting that extracellular zinc can be drawn in to fuel the hosts zinc poisoning strategy

This synergy is likely mediated by enhanced internalization resulting from the co-engagement and heterodimerization of HER2 and HER3 by the single Bispecific molecule, which aligns perfectly with the core rationale for developing BsADCs

Magr, A

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