Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan deuterium-labeled-ether SNAP-tag is a self-labeling protein

SNAP-tag is a self-labeling protein derived from human O6-alkylguanine-DNA-alkyltransferase

NCCC#CC1=CC=C2C(=O)N(C3CCC(=O)NC3=O)C(=O)C2=C1 Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

438 SMILES OCCCCCCCC1=CC=C2C(=O)N(CC2=C1)C1CCC(=O)NC1=O Purity (HPLC) >= 95% Shipping Conditions Room temperature Storage Conditions Refrigerated Shelf Life 12 months after the date of delivery Regulatory Statement For Research Use Only

Molecular Weight Cannot read molecule file

CA-amide-PEG4-Biotin is a Biotin-HaloTag ligand that enables rapid labeling of Halo-tagged proteins and their efficient isolation via streptavidin pull-down

Mal-Propionyl-PEG8-Val-Cit-PAB(m-PEG4)-Exatecan deuterium-labeled-ether SNAP-tag is a self-labeling proteinSOLU KNEX cleavable linker features a Val Cit dipeptide. The conventional maleimidocaproyl (MC) unit is replaced by Mal Propionyl PEG8 moiety to enhance aqueous solubility. The Mal Propionyl group may also improve retro Michael addition stability during antibody conjugation. m PEG4 is attached to the commonly used self immolative para aminobenzyl (PAB) moiety to increase aqueous solubility. The payload is Exatecan, a highly potent topoisomerase I