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It is generally believed that chloasma has much to do with sun exposure, but UV is not always necessary for the development of chloasma and there are other factors involved in promoting its development (142)

300 While AXIN1 is more frequently mutated in HBV-related HCCs (18%) than in HCV-related or non-viral HCCs (14% and 8%, respectively)

Rossi et al

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