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As a specialized glutathione peroxidase containing selenocysteine substituting cysteine, GPx4 plays an irreplaceable role in maintaining cell membrane integrity and protecting cells from oxidative damage by specifically reducing phospholipid hydroperoxides

These examples highlight the potential of incorporating redox pathway inhibitors in cancer treatment to improve patient outcomes [68-70]

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Activation of growth hormone secretagogue receptor induces time-dependent clock phase delay in mice

In addition, an enhanced 2-hydroxilation of estrogens, E 1 and E 2 , was associated with reduced risk of postmenopausal breast cancer [22]