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A reasonable candidate is someone who: Is already following a structured, clinician-supervised nutrition and activity plan Has a documented B12 deficiency or a condition that impairs B12 absorption Cannot tolerate GLP-1 medications, or is not a candidate for them Declines prescription pharmacotherapy and wants a non-stimulant, non-surgical adjunct Understands because the clinician has said so plainly that the injection is a supporting player A poor candidate is someone who wants the shot instead of the program

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J Am Chem Soc 144:701708 Her J, Zheng H, Bunting SF (2024) RNF4 sustains Myc-driven tumorigenesis by facilitating DNA replication