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Under physiological conditions, -synuclein aggregates are identified by autophagy adaptors like p62, incorporated into autophagosomes, and subsequently delivered to lysosomes for degradation by acid hydrolases, including cathepsins B and D

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[DOI] [PMC free article] [PubMed] [Google Scholar] 5.Staehelin LA

Supplementation, especially with methylated forms of B vitamins, may be beneficial for many men in this age group to support energy levels and hormonal health