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The aim of the study was to evaluate the effect the dual action on GPBAR1 and RORt, by the administration of Allo-LCA, in preventing the development of NASH inflammation and fibrosis

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The mainly chromosome-encoded response to chloromethane involves gene clusters associated with oxidative stress, production of reducing equivalents (PntAA, Nuo complex), conversion of tetrahydrofolate-bound one-carbon units, and central metabolism