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After this period, your provider may recommend: A 1-2 month break before resuming Continued treatment with periodic monitoring Dose adjustments based on your response Long-term use beyond 6 months should include periodic lab testing (IGF-1 levels, metabolic panel) and provider evaluation

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The simultaneous activation of these G protein receptor signaling pathways on the islet cells may lead to additional antagonistic or synergistic interactions, but this is unknown