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Vitamin B12-induced reduction of platelet monoamine oxidase activity in patients with dementia and pernicious anaemia

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Sands BE, Schreiber S, Blumenstein I, Chiorean MV, Ungaro RC, Rubin DT

ClinicalTrials.gov (2008) 8

While these immediate effects can be encouraging, they are often short-lived unless supported by regular injections and other complementary treatments or lifestyle changes

Genetic and pharmacologic NNMT suppression reduces adiposity and improves metabolic readouts in preclinical models, with supportive cellular data showing increases in NAD and SAM and suppression of lipogenesis