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doi: 10.1038/s41572-019-0128-6

If you have an open device, youll need to replace the coil sometimes

Studies of this phenomenon have shown that macrophages are activated by factors such as cigarette smoke extracts and release inflammatory mediators such as TNF-, CXCL1, CXCL8, CCL2, leukotriene (LT) B4 and reactive oxygen species (ROS), etc., which mediate the inflammatory response ( Figure 2 Macrophages have different phenotypes with different activation pathways that lead to different organismal responses

In severe cases, they can cause blood poisoning and shock