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This disparity underscores a critical knowledge gap that must be resolved before confident, evidence-based clinical adoption can be justified

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Overactivation of the ECS in Obesity Obesity and coexisting disorders such as insulin resistance, hypertension, and hypertriglyceridemia lead to the development of metabolic syndrome and type 2 diabetes (75)

Comparative genomic analyses of 17 clinical isolates of Gardnerella vaginalis provide evidence of multiple genetically isolated clades consistent with subspeciation into Genovars