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This cream is not meant to treat large areas

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Kawashima Y, Kodera Y, Singh A, Matsumoto M, Matsumoto H (2014) Efficient extraction of proteins from formalin-fixed paraffin-embedded tissues requires higher concentration of tris(hydroxymethyl)aminomethane

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This is the first placebo-controlled randomised, double-blind trial of a tablet containing the combination of ALA, SOD, B12, and ALC as a food supplement that investigated the efficacy of the tablet on all three major forms of chronic generalized DN, i.e., peripheral sensorimotor neuropathy, autonomic neuropathy, and painful neuropathy