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Emerging research continues to highlight that these conditions are multi-systemic, often driven by a combination of viral persistence, immune dysregulation, and underlying toxic burdens like heavy metal accumulation

Drug Metab Dispos 32(5):484489 Scandlyn MJ, Stuart EC, Rosengren RJ (2008) Sex-specific differences in CYP450 isoforms in humans

Proc Natl Acad Sci USA 95 , 1321713220 (1998)

Cerebral glycolysis: a century of persistent misunderstanding and misconception

Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes

This improvement was partially attributed to the inhibition of the miR-34a/SIRT1/p53 pathway [119]