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Similar observations of increased numbers of DNA damage, like DNA double strand breaks, were shown in different ALS subgroups

Trends Immunol (2013) 34:32935

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It is mostly believed that DMF exerts its therapeutic effects through antioxidant and anti-inflammatory pathways (Figure 1)

Compos de trois acides amins (cystine, glutamine et glycine), le glutathion joue un rle cl dans la dtoxification du corps, notamment au niveau du foie, en liminant les substances toxiques

Seki H, Takayama H, Aimi N, Sakai S, Ponglux D (1993) A nuclear magnetic resonance study of the eleven stereoisomers of heteroyohimbine-type oxindole alkaloids