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Both doses led to an increase in maximal respiration and ATP-linked respiration in HC cells, while mitochondrial biogenesis and oxidative phosphorylation gene expression remained unchanged, suggesting that UA specifically enhances mitochondrial respiration to improve chondrocyte metabolic function

Increased oxidative stress in patients with depression and its relationship to treatment

Sleep-wake disturbances and frailty in community-living older persons

doi: 10.7868/s0026898413030166

C., Zelli, D., Svenningsson, P., McEwen, B

Under physiological conditions, laminar blood flow keeps the vascular wall in a quiescent state, with a predominance of NO signaling, which inhibits inflammation, cellular proliferation, and thrombosis [55, 56]