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doi: 10.1038/45230 47 KojimaM.KangawaK

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This also results in the formation of advanced glycosylation end products (AGEs), which are modifications of proteins or lipids that become non-enzymatically glycosylated when exposed to aldose sugars and oxidative stress (213-215)

Some patients report a yellow tinge to the skin due to mild jaundice from ineffective erythropoiesis

Redistribution of the chromatin remodeler Brg1 directs smooth muscle-derived adventitial progenitor-to-myofibroblast differentiation and vascular fibrosis

It may be concluded that the hydroxyl groups at both the C7 and C8 positions could completely change the inhibitory mechanism of the isoflavones from the reversible competitive to the irreversible suicide form 52