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400,401 Coupled with its role in regulating cell proliferation, AKT signaling is involved in regulating glucose homeostasis and lipid metabolism

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It also serves as a cofactor for numerous enzymes in the nervous system, including iron-sulfur clusters in the mitochondria, heme-containing proteins, such as hemoglobin or neuroglobin, and oxygen-containing diiron enzymes, such as ribonucleotide reductase (Alrouji et al

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