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These results implicate that PGD 2 and PGE 2 play important roles in FCMD pathogenesis and that novel hematopoietic PGD 2 synthase inhibitors and steroids used in DMD may also have therapeutic utility in FCMD

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In addition, measurement of expression of URA3 in the pGSH1-URA3 strain according to levels of GFP-tagged Ura3 revealed a significant upregulation by 5-FOA (Figure S4C)

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