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GHK-Cu reverses follicle miniaturisation by stimulating keratinocyte proliferation and expanding the follicle base (Pickart et al., 2012)

Extracellular collagenases and the endocytic receptor, urokinase plasminogen activator receptor-associated protein/Endo180, cooperate in fibroblast-mediated collagen degradation

Although this architecture does not entirely impede the initial infiltration of immune cells into the tumor tissue, it significantly impedes their subsequent migration towards the tumor core and critical structures such as islets (79) ( Figure 2 )

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