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A commonly used regimen is a loading phase of 25 mg per week (subcutaneous injection) for 46 weeks, followed by a maintenance dose of around 2 mg every 12 weeks

It enhances adipose tissue browning (conversion of white fat to more metabolically active brown fat)

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Discussion In this study, we performed FACS-based genome-scale CRISPR screens to identify critical modulators of hepatic surface LDLR abundance

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