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The fatty acid metabolism process involving mitochondria includes fatty acid synthesis (FAS) and FAO

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Culturing primary B-ALL cells or Reh lymphoid cell line with bone marrow-derived MSCs under hypoxic conditions induces a higher expression of HIF-1 and therefore an acquisition of the glycolytic phenotype of leukemic cells, which in part is due to signaling-regulated by the AKT/mTOR pathway induced by stromal cells

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