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Azumi H, Inoue N, Takeshita S, Rikitake Y, Kawashima S, Hayashi Y et al

5: Montero AJ, Jassem J

It has been reported that the GSTP1 Val105 not only has a significantly lower affinity for glutathione, but also is more sensitive to inhibition by Hg species 38

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A few small-scale studies have linked IGF-axis polymorphisms to cardiometabolic traits ( In parallel, successful clinical translation will require rigorous evaluation of extra-cardiovascular safety profiles (e.g., metabolic and oncogenic risks) and careful assessment of optimal combination strategies with existing vasodilatory and antifibrotic therapies