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Astrocyte and microglial release of these cytokines may be a main contributing factor to epileptogenesis

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2.4 Toxicity mechanism of iron-dependent death 2.4.1 Definition and core regulation of ferroptosis Ferroptosis is a regulated form of cell death characterized by the accumulation of iron-dependent lipid peroxides (53)

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The suppression of mitochondrial ROS generation in macrophages effectively curtails inflammasome activation (165)

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