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A.AljohaniG.BinSabtM.AhmedI

Cell Physiol Biochem 38:22302238

Malonyl-CoA accumulates in the absence of fatty acids in these cells in an ACC-dependent manner (Supplemental Figure 4D), and labeling paralleled that of acetyl-CoA, suggesting that glucose-derived carbon may feed into an extramitochondrial acetyl-CoA pool in these cells (Figure 5C)

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is supported by NIH (R00CA248838, DP2GM159178), the Cancer Prevention and Research Institute of Texas (CPRIT RR210059) and the American Cancer Society (ACS RSG-24-1255384-01)

The overweight and obese status in diabetic participants may be implicated to cause an impaired cell response to insulin