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Importantly, treatment with marmelosin at both doses demonstrated a significant attenuation of these pathological changes, encompassing a reduction in interstitial inflammation, amelioration of pancreatic follicle cell swelling and necrosis, and a notable improvement in the organization of islet architecture (Figure 10AD)

Pediatric, prothrombin time/INR should be periodically monitored to determine if the dose of warfarin needs to be adjusted

Prajapati C, Tripathi PN, Sood S, et al

It is a natural and slow process

Journal of Physiology, Paris , 87 (5), 313327

In the future, disease management might rely on severity scores that incorporate prognostic factors, bowel damage assessment and non-invasive close monitoring of disease activity to reduce the severity of complications