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MT1-MMP deficient mice exhibit various age-associated phenotypes and die from cachexia at around 34 weeks of age 9,10,11

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In AML, inhibition of mitochondrial translation has been shown to overcome venetoclax resistance through activation of the ISR (123)

and if the relative abundance of the qualitative ion(s) for each component in the sample is compared with the relative abundance of the corresponding qualitative ion(s) in a standard working solution of similar concentration, and the deviation does not exceed the range specified in the table below, then the corresponding analyte can be determined to be present in the sample