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However, despite the recent approval of the first drug, resmetirom, for the management of metabolic dysfunction-associated steatohepatitis, decades of target exploration and hundreds of clinical trials have failed, highlighting the urgent need to find new druggable targets for the discovery of innovative drug candidates against MASLD

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Currently, topical treatments are accompanied by significant side effects, indicating that exploring new therapeutic approaches is critical 34

Canonical autophagy machinery plays a crucial role in ferroptosis 48

Chemistry and Biodiversity 17, e1900603.CrossRefGoogle Scholar Kaczor-Keller, KB et al

With the help of advanced technology, including echocardiography and event monitoring, they are more than able to handle serious heart issues as well