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Ferroptosis, an oxidative stress-dependent regulated cell death modality, is potently triggered by oxidative stress, a mechanism particularly critical in ocular pathologies (159).Accumulating evidence implicates ferroptosis in retinal neurodegeneration and DR pathogenesis, supporting oxidative stress as a central bridge linking ferroptosis to DR progression (160, 161)

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Life Sci 284:119911 Sayed AM, Abdel-Fattah MM, Arab HH, Mohamed WR, Hassanein EH (2022) Targeting inflammation and redox aberrations by perindopril attenuates methotrexate-induced intestinal injury in rats: role of TLR4/NF-B and c-Fos/c-Jun pro-inflammatory pathways and PPAR-/SIRT1 cytoprotective signals

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However, they are closely examining whether self-medication and unsupervised anti-ageing regimens were a major factor.The final medical report is awaited.Shefali Jariwala is survived by her husband

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