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In embryos or larvae, initial screening evaluates gross developmental endpoints such as mortality, malformation rates, and behavioral alterations

Erythropoietin has been shown to inhibit ferroptosis by reducing iron overload and lipid peroxidation both in vitro and in vivo (68)

Further integrative analysis applied weighted gene co-expression network analysis (WGCNA) to identify co-regulated gene modules within each brain region

Human T-cell lymphotropic virus type 1-infected T lymphocytes impair catabolism and uptake of glutamate by astrocytes via Tax-1 and tumor necrosis factor alpha

*Correspondence: Yanjun Li, [email protected] These authors have contributed equally to this work and share first authorship Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

doi: 10.1016/j.freeradbiomed.2020.07.012 330 SaddikiHFayosseACognatESabiaSEngelborghsSWallonDet al