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Septic shock has a high cost of treatment, with an increasing incidence and high mortality.1 Brazilian data show that in the period from 2006 to 2015, the incidence grew by 50.5%, representing a rate of 47.4/100,000 people per year, with a mortality rate ranging from 43% to 60%.2 The pathophysiology of sepsis is complex and still not fully understood

Estrada et al., 2003, 2006

We evaluated liver enzymes, lipid profile, fasting plasma glucose, C-reactive protein (CRP), tumor necrosis factor (TNF)-, homeostasis model assessment (HOMA)-IR, body mass index, and histological scores

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Future work should focus on better elucidating the molecular mechanisms behind this treatment