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In the absence of an appropriate binding partner, Aurora-A adopts an inactive conformation, and the surface of the kinase has several hydrophobic pockets that provide binding sites for combinatorial interactions

While metformin primarily controls fasting blood sugar, acarbose regulates postprandial glucose levels

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Before the meeting, more than a half-dozen people with connections to the peptide industry were added to the panel, including doctors, pharmacists or consultants

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A meta-analysis confirmed that avanafil had comparable efficacy with sildenafil, vardenafil and tadalafil [411]