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A healthy gut microbiota interacts with intestinal epithelial cells to promote T-cell differentiation, particularly the production of regulatory T cells, which help maintain immune tolerance

Front Endocrinol 3:171 Takeuchi K, Amagase K (2018) Roles of cyclooxygenase, prostaglandin E2 and EP receptors in mucosal protection and ulcer healing in the gastrointestinal tract

Stem Cell Res Ther 9(1):216 Huang Y, Zhu M, Liu Z, Hu R, Li F, Song Y, Geng Y, Ma W, Song K, Zhang M (2022) Bone marrow mesenchymal stem cells in premature ovarian failure: mechanisms and prospects

It should be noted that the effect of B12 was pleiotropic, that is, it regulates several metabolic or intracellular signaling pathways maladjusted by COVID-19 despite the glucocorticoid treatment that patients received during hospitalization

These properties contribute to the prevention of chronic diseases and support therapeutic strategies

2) May Support Liver Health The liver is the major organ involved with detoxifying the body from medications and substances such as alcohol