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X-ray and cryo-EM data have illuminated their overall conformations, differences in functional motifs crucial for receptor activation, and intricate details of the ligand-binding pockets

CONGENITAL INTRINSIC FACTOR DEFICIENCY OR FUNCTIONAL ABNORMALITY An affected child usually presents with megaloblastic anemia in the first to third year of life

A multi-crystal method for extracting obscured crystallographic States from conventionally uninterpretable electron density

Unlike many peptides that require injection or intranasal delivery, GSB-106 has demonstrated efficacy through oral administration in animal models

No trials, no approval

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