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Systemic treatments with tyrosine kinase inhibitor and platinum-based chemotherapy in patients with unresectable or metastatic hepatocholangiocarcinoma

The study was conducted in four groups of thirty SpragueDawley rats (control, control + whey protein concentrate (WPC), MTX, MTX + WPC)

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Whether the hyperprolactinemia, amenorrhea, and galactorrhea were secondary to the hypothyroidism or were independent problems was at first unclear