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In congenital pernicious anemia, low serum total B12 concentrations arise from B12 malabsorption caused by mutations in a gene (GIF,CBLIF) and defects in the synthesis of intrinsic factor

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262 A trial involving 30 fibromyalgia patients reported 200 mg of intramuscular plus 400 mg of oral SAMe daily for six weeks was more effective than transcutaneous electrical nerve stimulation (TENS) for reducing tender points, pain and fatigue, and depression and anxiety scores